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  Histamin Anti histamin Wisnu   Setyari   J  HISTAMIN    Biogenik   amin   endogen yang   di   sintesa   dlm   sel    L   -   histidin    –    histidin    decarboksilase    Histamin    Disimpan   dan   dikeluarkanoleh   :    Mast cell : skin , respiratory tract , GI tract    Basophil   dalam   darah    CNS   dan   peripheral NS     Histamin   mempunyai   peran   padakeadaan    fisiologis   dan    patofisiologis     Fisiologis    :    Merangsang   sekresi   asam   lambung   dan   pepsin (H2)    Neurotransmiter    (H3)   pada   sistem   syaraf    pusat   danperifer 
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